In 1918, Lense and Thirring discovered in general relativity the gravitomagnetic effect on the Moon’s orbit around Earth in the gravitational field of the rotating Sun. This Lense-Thirring frame dragging effect is important in the understanding of astrophysical phenomena. It is also important in finding the matched templates for detecting gravitational waves. Lense-Thirring precession of the orbits of LAGEOS satellites was experimentally verified. The frame-dragging on the quartz gyros on board the Gravity Probe B drag-free satellite is successfully measured. With the development of laser interferometry and atom interferometry, the precision of laser ring gyros and atom gyros improves quickly. A number of large-scale earth-based ring gyros with the aim for geophysical applications, and for measuring the Lense-Thirring effects are under development. Large-scale atom gyros have also been seriously proposed.