The IEEE Brain Initiative Workshop will highlight the development of novel technological innovations, including engineered neuro-materials based implants, opto-genetics, to treat and monitor, traumatic brain injury, cognitive brain impairments, stroke and spinal cord injury etc. We also highlight translational clinical research on human-machine interface systems to significantly restore, and enhance, the impaired sensory functions and motor systems. Furthermore, global neuro-technology industry trends, nano devices, computational advances, and stem cell engineering for the treatment of neurological diseases, from the molecular to systemic levels, will be discussed.