Ambient intelligence can help, transform, and enhance the way people with disabilities perform their activities of daily living, activities that would otherwise be difficult or impossible for them to do. However, despite the increasing trend toward the development of new assistive technologies to help people with disabilities, no real adoption tendency has been observed yet, regarding the targeted user groups. Indeed, users’ impairments and particularities are so diverse, that implementing complex technological solutions — mandatory for user adaptation — represents a major challenge in terms of universal design. In such a context, the main objective of this workshop is to investigate new solutions to scientific problems occurring in the various topics related to artificial intelligence applied in the domain of impaired people assistance.