This workshop is for investigators of all disciplines who are engaged in, or who are interested in, research focused on detection and imaging techniques that are based on non-conventional emission signals, such as x-ray fluorescence, x-ray luminescence, and Cherenkov radiation, development of radiation-induced therapeutic agents that emit the above radiation signatures, and application of non-conventional emission tomography techniques using the above radiation signatures for confirming, characterizing, and monitoring therapeutic delivery. It is intended the workshop presentations and discussions will promote multidisciplinary research on development of novel radiation-induced and image-guided therapeutic delivery processes and help identify uses for detector technologies and imaging techniques in this context. If you are interested in presenting in this workshop, please send an email to one of the organizers indicating your interest and potential topic. Please indicate your interest as soon as possible and preferably no later than July 24, 2017.