“Health, Collaboration, Innovation, and Sustainability” are the main melody of our era. The Internet, including widespread use of mobile and wireless devices, has grown as a ubiquitous infrastructure to support the fast development of diversified services. The advents of the Internet of Things, cyber-physical systems, and big data are creating a new technology revolution, i.e. next generation of internet or industry 4.0. The integration of the digital world with the physical environment makes our world more intelligent and efficient. Large-scale networked intelligent systems require higher cooperation and interoperation of heterogeneous IoT platforms. Therefore, this conference focuses on emerging models, paradigms, technologies and novel applications related to Internet-based distributed systems, including Internet of Things, cyber-physical systems, wireless sensor networks, next-generation collaborative systems, extreme-scale networked systems, and cloud-based big dada systems. The target audience includes researchers, PhD students and practitioners that have a general interest in the different aspects of the Internet and Distributed Computing Systems with a more specific focus on practical and theoretical aspects of the cyber-physical systems built with the integration of computer networks, distributed systems, wireless sensor technology and innovative human-computer interfaces. The conference also has a special interest in novel applications that facilitate the design, deployment and management in complex real-life systems, such as e-Health, transport and logistics, smart cities and manufacturing.