The FCST 2010 conference provides an open forum for engineers and scientists in academia, industry, and government to address all resulting profound challenges including technical, safety, social, legal, political, and economic issues, and to present and discuss their ideas, results, work in progress and experience on all aspects of computer science and technology. FCST had been held four times. They are as follows: Aizu-Wakamatsu, Japan, November 2006 (FCST 2006, Indexed by Ei Compendex); Wuhan, China, November 2007 (FCST 2007, Indexed by Ei Compendex); Nagasaki, Japan, December 2008 (FCST 2008, Indexed by Ei Compendex); Shanghai, China, December 2009 (FCST 2009, Will be indexed by Ei Compendex). The accepted papers have to be presented orally at the conference and will be published in proceedings of the FCST 2010 conference by IEEE Computer Society CPS. All papers in the FCST 2010 proceedings are expected to be indexed by Ei Compendex. The selected best papers will be considered to be published in special issues of international journals (Indexed by Ei Compendex or SCI-E). Now, International Journal of Parallel, Emergent, and Distributed Systems is being contacted.