The symposium intends to promote the shifting of the materials research paradigm from the traditional trial and error approach to the Materials Genome Initiative (MGI) and Integrated Computational Materials Engineering (ICME) approach, with a view of accelerating the design and application, and at the same time reduce the cost of the development of new materials, by integrating multi-scale modeling and simulation with experimental efforts. Contributions are welcome on, but not limited to the following topics:

• MGI and ICME methodology, including high-throughput computation, sample preparation and characterization method and database technology;

• First principles prediction of the fundamental properties of alloys, high-throughput evaluation of the effects of alloying elements and impurities;

• Atomistic simulation of dynamic process, such as deformation, defects formation and interaction, their effects on the mechanical behavior of materials, including strength, ductility, fatigue, fracture, creep and wear, etc;

• Meso-scale simulation of phase transformations and microstructural evolution during thermo and thermo- mechanical treatment, phase diagram computation, thermodynamics, kinetics and microstructure optimization;

• Process simulation for thermo-mechanical processing, melting, casting, welding, 3-D printing and machining, crystal plasticity FEM simulation, defects and distortion prediction, process optimization;

• Structure, stability and migration of grain boundary and other interface during deformation and phase transformation; nucleation, growth and interaction of dislocation, deformation twin, and point defects formation, their effects on the properties of materials, such as strength, ductility, electrical, optical and magnetic behavior of materials;

• Modeling of nano- and amorphous materials, gradient and architecture materials, high-entropy alloys, their deformation, stability, shear localization and flow. Hardening, degradation and phase transformation driven by radiation, electrochemical, oxidation, corrosion and mechanical force;

• Synergy between modeling and experiments, validation and verification of results of simulations from atomic to acroscopic scales, and stimulating experimental work seeking computational solutions.