70 / 2018-06-27 16:49:16

Nepenthes inspired ultra-slippery textured surface for anti-sticking of soft tissue

minimally invasive surgery,electrosurgical scalpel,bio-inspired surface,anti-sticking

全体主题 > ii. Biomaterials and formulation of novel “bioinks” for tissue-specific applications

Minimally invasive surgery with the advantages of less trauma, slight pain and quicker recovery has gradually become the mainstream of surgical operation. Surgical tissue cutting and hemostasis are usually accomplished via energy-based surgical instruments such as monopole electrode and electric coagulation. Due to high working temperature, soft tissue sticking of surgical instruments in minimally invasive surgery can increase the difficulty of operation and easily lead to medical malpractice. In this paper, inspired by continuous and directional water transport of Nepenthes peristome, we put forward a new strategy of liquid thin film induced anti-adhesion based on revealing the ultra-slippery anti-adhesion mechanism. Bionic ultra-slippery textured surface was fabricated and applied on the surfaces of surgical instruments. Micro arrayed pillars and pits with diameter of 60-200μm and 15±5μm depth were fabricated in the surface of monopolar electrosurgery and unipolar electrocoagulation via photolithography-assisted chemical etching process. Silicone oil, with good biocompatibility and high temperature resistance, was chosen as the infused liquid after the textured surfaces were OTS modified. The anti-sticking effects of prepared slippery surface were evaluated compared to the untreated surfaces. Results show that the as-prepared bionic ultra-slippery textured surface has a remarkable anti-sticking performance with lower sticking force and minimal soft tissue sticking mass. The bio-inspired ultra-slippery textured surface satisfied the requirements of energy conservation minimally invasive surgical equipment anti sticking technology.