With the development of traffic road construction this paper made full use of finite difference method to study the dynamic response of high slope and stability analysis. The dynamic response of the slope is discussed by a large number of dynamic numerical analysis. It is found that the characteristics of the velocity, velocity and acceleration of the slope dynamic response are distributed on the slope profile by the three magnification coefficient. The subgrade has a significant effect on the intensity of seismic wave along the slope.The mechanical properties and response of slope under dynamic load are studied. It is helpful to further reveal the law of dynamic load in the subgrade.