There are two major tectonic settings for Iranian VMS deposits (arcs and suprasubduction zones), with arcs (volcanic primitive arcs, arc/intra-arc rifts and back-arc basins) being the most important. All of the VMS deposits of the Sanandaj-Sirjan zone (SSZ) and Urumieh-Dokhtar magmatic assemblages (UDMA) formed within Mesozoic and Tertiary magmatic arcs, respectively, that developed during subduction of the Neo-Tethyan crust beneath the Iranian plate. Suprasubduction zone or intra-oceanic back-arc spreading or mature back-arc rifting are recognized in the Neo-Tethys domain in Iran, and these host several Cu-rich VMS deposits. The host rock sequences for all deposits can be divided into three groups: (1) bimodal calc-alkaline; (2) bimodal tholeiitic; and (3) tholeiitic basaltic.