The metal deposits in the Tethyan metallogenic domain (TMD) are much more poorly documented as a synthesized classical metallogenic model. Here I try to classify spatially the major metal deposits in the eastern TMD into seven areas basing on previously published data and metallogenic models.These areas are: Turkey, Iran, Five Central Asian countries, Afghanistan, Pakistan, Tebet-Sanjiang in China, Indochina, respectively; According to published geochronological data , the major metal deposits can be merged into six main metallogenic epochs: the Late Devonian-Early Permian, Late Permian, Middle-Late Jurassic, Middle Cretaceous, Late Cretaceous-Early Paleocene ,middle Eocene-Present time, which were related with the tectonic process from opening, subduction and Cretaceou of the Paleo-Tethyan, and Neo-Tethyan Oceans respectively.Of these deposits, they seperated from continuous belts to scatter distribution, which is closely related to the tectonic-metallogenic process.