At present, major national space missions such as manned spaceflight, lunar exploration, planetary exploration and manned lunar landing are coming into a situation of high density, high difficulty and high intensity. Traditional space flight control mission planning theories, methods and tools have become a bottleneck that seriously restricts the optimization and improvement of flight control working mode. In view of the shortcomings of the traditional working mode of nominal plan document, the application of Model-Based System Engineering (MBSE) in the field of space flight control is investigated, and a mission planning method based on MBSE for aerospace flight control is proposed. It takesthe input of flight control mission requirement analysis and the output of planning product generation and verificationas the starting point.By business scenario process combing, mission planning model constructing, system function architecture design and other aspects, the proposed method focuses on the modelization of measurement and control resource allocation, flight control event scheduling and automatic conflict resolution, which is aimed at achieving hierarchical model construction of flight procedures and automatic generation of planning products.