97 / 2023-07-15 10:43:35

Effect of amoxicillin on the succession of microbial communities at the core of nitrogen transformation and ARGs during sludge composting

Composting,Nitrogen transformation,Bacterial community,Antibiotic,Antibiotic resistance genes

Composting is a highly method for utilizing waste materials. sludge is often accompanied by unpleasant odors and contamination from heavy metals and pathogens, is presently found to contain varying levels of antibiotics and antibiotic resistance genes (ARGs) in the global environment. Improper treatment of sludge may result in subsequent contamination of soil and water sources. Nevertheless, sludge is abundant in nitrogenous nutrients. Therefore, sludge composting can improve sludge resource efficiency and mitigate the presence of ARGs.

Nitrogen serves as a crucial nutrient source for microorganisms and plays a key role in promoting the composting process. Although composting can reduce antibiotic and ARGs to some extent, the change patterns of ARGs and the succession of microbial communities associated with the nitrogen transformation during composting need further investigate. Therefore, it is imperative to conduct an investigation into the biological patterns pertaining to the transmission of resistance genes and the nitrogen cycle in sludge composting. Amoxicillin effects on the succession of microbial communities at the core of nitrogen transformation and ARGs during sludge composting. This study further established the response relationship between inorganic nitrogen components, amoxicillin-associated ARGs and their potential host bacteria during sludge composting. The key microorganisms could be regulated to reduce ARGs and the loss of nitrogen during sludge composting.