A novel four-element linear array of squared microstrip patches antenna that must be reconfigured to identify and visualize tumors within the human brain is proposed. Polyimide is selected as a substrate because of its low dielectric constant, flexibility, dimensional, thermal, and high-temperature stability. First, a patch antenna with a small reconfigurable four-element linear array of squared microstrip patches that operates at the ISM band (2.4-2.4835GHz). For square patch antennas with coaxial feed are designed for resonant frequencies. The antenna is then surfaced on a human head phantom model, which has six homogeneous layers: skin, fat, skull, and brain. The tumor is implanted in several spots in the human head phantom model. The tumor location can be determined by rotating the antenna array to scan the head. The purpose of antenna arrays is to provide sufficient energy to penetrate human tissues. It is simulated using the HFSS software. Based on the simulation of a square antenna unit, a four-element antenna array is presented. The design method for the feed network of the array is given. The measured findings proved the antenna's polarisation reconfigurability for the operating band. The proposed antenna is S-band compatible.