Screening is an important part of mineral processing. A large-scale dry screening method (the 1/0.8 mm classification of linear vibrating flip-flow screen) is proposed, which break through the lower limit of traditional large-scale dry deep screening. When the treatment capacity reached 4.47 t/(h·m2), the screening efficiency reached 70.56%, and the total mismatched material content of the screening machine was 8.55%. Based on this, a combined process of dry–wet two-stage desliming, gravity separation, and flotation for spodumene raw ore is proposed. About theoretical research, the screening probability model of flip-flow screening was established. The screening probability of particles was mainly determined by the average contact-mesh probability and screen-penetrating probability. The particle-size effect of flip-flow screen was clarified. As the lower limit of classification decreases during the screening process, the dominant particle-size fraction becomes more significant. When the composition of the particle-size obeyed a normal distribution and with the increasing dispersion degree, the average particle-size fraction was at a distance from the near-screen particle-size, and the comprehensive separation index was higher.