In order to improve the safe operation of the multiphase flow of the submarine transportation system and promote the further development of deep-sea oil and gas resources, based on the high-pressure reactor and particle size measurement system, the evolution and development of different hydrate deposits have been studied. The research results show that the migration and continuous transformation of pore water in the deposits layer constitute the main evolution process of the hydrate deposits. Based on the thickness change of the deposits layer and the theory of porous media seepage, a model of the pore water migration rate under different water contents is established. The particle size distribution in the system has an important influence on the depositis morphology and evolution.