摘要详情
19 / 2021-09-27 22:56:34
Quantification of pectinate muscles inside left atrial appendage from CT images using fractal analysis
left atrial appendage; pectinate muscle; region growing; fractal dimension
终稿
Abstract—Objective: Atrial fibrillation (AF) is a common cause of cerebral infarction resulting from thromboembolism. The left atrial appendage (LAA) is the main location of thrombus formation. The objective of this study is to quantify the morphological structure of pectinate muscle inside LAA using fractal analysis.
Methods: In this study, fractal analysis of pectinate muscle consists of two steps. The first step was image segmentation using the region growing method based on grayscale to extract the border of LAA. Then the fractal dimension (FD) of the border of LAA was calculated using box-counting method. This quantitative analysis was assessed via both healthy volunteers (n=7, age: 61±5, male, 5) and thrombus patients (n=3, age: 63±6, male, 2). Mann Whitney U test was used for statistical analysis.
Results: For image segmentation, the region growing method successfully segmented the borders of LAA for all volunteers and patients. The FD values of healthy groups and thrombus groups were 1.179±0.005 and 1.113±0.006, respectively. The mean FD value of healthy groups was higher than in thrombus groups (p < 0.0001).
Conclusion: Fractal analysis provides an effective measurement to quantify the complexity of pectinate muscle inside LAA and has the potential to distinguish thrombus patients from health.
Methods: In this study, fractal analysis of pectinate muscle consists of two steps. The first step was image segmentation using the region growing method based on grayscale to extract the border of LAA. Then the fractal dimension (FD) of the border of LAA was calculated using box-counting method. This quantitative analysis was assessed via both healthy volunteers (n=7, age: 61±5, male, 5) and thrombus patients (n=3, age: 63±6, male, 2). Mann Whitney U test was used for statistical analysis.
Results: For image segmentation, the region growing method successfully segmented the borders of LAA for all volunteers and patients. The FD values of healthy groups and thrombus groups were 1.179±0.005 and 1.113±0.006, respectively. The mean FD value of healthy groups was higher than in thrombus groups (p < 0.0001).
Conclusion: Fractal analysis provides an effective measurement to quantify the complexity of pectinate muscle inside LAA and has the potential to distinguish thrombus patients from health.
重要日期
-
会议日期
11月13日
2021
至11月14日
2021
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09月30日 2021
报告提交截止日期
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11月14日 2021
注册截止日期
主办单位
IEEE北京分会
中国生物医学工程学会医学物理分会
中国电子学会生命电子学分会
中国生物医学工程学会医学物理分会
中国电子学会生命电子学分会
承办单位
中国科学技术大学
安徽省生物医学工程学会
安徽省生物医学工程学会
联系方式
- Mrs. Yang
- ic******@ustc.edu.cn
- +86********
历届会议
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2017年11月04日 中国 Beijing,China
2017 International Conference on Medical Imaging Physics and Engineering -
2017年11月03日 中国 海淀区
2017 IEEE 国际医学影像物理和工程大会 -
2013年10月19日 中国 沈阳市
2013 IEEE国际医学影像物理和工程大会暨第七届中国医学影像物理学术年会
