Chao Shi / Wuxi Center for Disease Control and Prevention
Yuan Shen / Wuxi Center for Disease Control and Prevention
Qian Geng / Wuxi Center for Disease Control and Prevention
We investigated the genotypic changes and epidemiologic features of norovirus outbreaks, as well as factors influencing the attack rate and outbreak duration in Wuxi from 2014 to 2018. A total of 74 norovirus outbreaks were reported in Wuxi from 2014 to 2018. The predominant norovirus genotypes in outbreaks have changed from GII.17 (20.3%) in 2014-2015 to GII.P16/GII.2 (40.5%) in 2017-2018. GII.P16/GII.2 in 2017-2018 season were more prevalent than GII.17 in 2014-2015 season (χ2 =4.741, P=0.029). 56.7% of outbreaks occurred in primary school. The reinfection rate of norovirus outbreaks was 16.2%. 66.7% of reinfection outbreaks were infected by variants different to previous infections. Outbreaks occurred in non-primary school settings(P=0.02) and that with setting suspension (P=0.025) experienced a higher attack rate. The outbreaks in primary schools(P=0.024), reinfection outbreaks (P=0.035) and longer report timing (P=0.001) declared a significantly longer duration. It is of great importance that the monitoring of norovirus outbreaks for the emergence of novel strains, along with responsive preventive and control interventions, should be strengthened in adults and school-age population, especially in primary students and preschool children.