The shape control is an important part to keep the plasma configuration. The Quasi-Snowflake configuration (QSF) could increase the flux expansion near the stick points. In EAST, the shape control scheme is using 12 PF coils to control the flux of several control points and the magnetic field of X-point. Due to the PF coils position, it is difficult to control each shape control points and X-point magnetic field by Single-Input Single-Output method. A numerical decoupling method for the Multi-Input Multi-Output (MIMO) system is required to solve this problem. Several different MIMO controllers in EAST are designed with different physical based response models include rigid model, perturbed equilibrium plasma response model in TOKSYS tools and CREATE-L model [1]. The SVD method has been used to decouple the system. Experiments are conducted with different MIMO controllers and the plasma response is observed for checking the response models. The preliminary results of MIMO plasma shape control for QSF configuration prove the potential for MIMO controller.