710 / 2019-05-06 09:43:37

Decoding metabolome in Arabidopsis and beyond

metabolome

全体主题 > Metabolism

The recent advances of genomics and metabolomics in plants accelerate our understanding about the function of plant metabolites, and the mechanism, regulation and evolution of their biosynthesis. The study decoding genome and metabolome is called as ‘Phytochemical Genomics’ as the new sector in plant science, which elucidates the genomic basis of diversity and function of plant metabolites [1]. In this presentation, I will report our recent studies [2,3] decoding the function of genome and diversity of metabolome in Arabidopsis thaliana and applications beyond the model plant. The topics include:
• A sophisticated strategy for decoding metabolome in diversified plant species including A. thaliana.
• A couple of examples for identification of genes and metabolites involved in the stress-responsive specialized metabolism in A. thaliana and crops/medicinal plants.

Key references
1. Rai, A., Yamazaki, M., Saito, K.: A new era in plant functional genomics. Curr. Opin. Sys. Biol., 15, 58-67 (2019)
2. Higashi, Y., Okazaki, Y., Takano, K., Myouga, F., Shinozaki, K., Knoch, E., Fukushima, A., Saito, K.: HEAT INDUCIBLE LIPASE1 remodels chloroplastic monogalactosyldiacylglycerol by liberating α-linolenic acid in Arabidopsis leaves under heat stress. Plant Cell., 30 (2018)
3. Tsugawa, T., Nakabayashi, R., et al.: A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms. Nature Methods, 16, 295–298 (2019)